PDC 505: Effective Use of Inhalation Dosimetry in Workplace Risk Assessments – NEW!

Kansas City Convention Center 

Room: 2505 B 

CM Credit Hours: 3.5 

In industrial hygiene, exposure is often used as a surrogate measure for dose. However, these terms are not synonymous. Breathing zone air concentration measurements are a focus of OEHS exposure assessments. The risk assessment includes a comparison of the measured concentration to an occupational exposure limit (OEL). Assessment for workplace aerosols includes: a) comparing total particulate results to inhalable fraction OELs; b) using total mass for exposures to mixed-phase or semi-volatile chemicals; and c) relying on OELs derived from animal toxicology studies. Inhalation dosimetry modeling (IDM) estimates internal doses based on aerosol physiochemical properties and human/animal physiological parameters. Advanced IDM approaches are being incorporated into exposure assessments, risk assessments, and interpretation of OELs. Such applications describe the relationship between external exposure and internal dose, extrapolations of animal studies to human equivalent concentrations, and how aerosol characteristics impact disease risk. This PDC will cover 1) the fundamentals of aerosol inhalation dosimetry; 2) current IDM approaches; and 3) future developments. Case studies and tools highlighting real-world examples will be used to reinforce the application of IDM for an advanced occupational risk assessment program.

*Please note: Only participants registering for two (2) half-day PDCs on the same day will receive a box lunch. **Please note: power strips will not be provided at each attendee's seat; however, charging stations for laptops will be provided in each course room.

• Aerosol Exposure Assessment Concepts and Characteristics
• OEL Derivation and Application Principles
• Inhalation Dosimetry Models and Methods
• Demonstrations and Hands-on Practice of Dosimetry Methods and Models.
• Applications of Dosimetry Tools for Risk Assessments
• Emerging topics 

Upon completion, the participant will be able to:

• Summarize the fundamentals of inhalation dosimetry modeling.
• Identify critical inputs and assumptions.
• Select inhalation dosimetry models based on use and their strengths and limitations.
• Develop an inhalation dosimetry modeling plan for risk assessments and OEL derivations.
• Apply IDM in real-world situations to improve risk characterization. 

Attendees should have a basic understanding of human health risk assessment, including exposure and dose, methods for OEL derivations, and interpretation of OELs. 

Attendees will gain an understanding of the connections between external exposure and internal dose which will allow for informed risk assessments. 

Inhalation dosimetry modeling can be utilized to assess the relevancy and selection of OELs, which impact controls and monitoring approaches. IDM can be used to understand the impact of controls by connecting exposure to dose. 

Intermediate

Laptop

Corporation/Company

All Industries

Aerosols & Airborne Particulates

Risk Assessment and Management

Group activities