B4: A Guide to Designing and Performing Exposure Simulation Studies

Rachel Zisook Moderator
Insight Exposure & Risk Sciences Group
San Francisco Bay Area, CA 
 
Heather Avens, PhD, MS, CIH Presenter
Insight Exposure & Risk Sciences Group
Lafayette, CO 
USA
 
Angela Shen, MPH Co-Presenter
Insight Exposure and Risk Sciences Group
Rancho Palos Verdes, CA 
USA
 
Maya Ghosh Co-Presenter
Insight Exposure and Risk Sciences Group
Boulder, CO 
USA
 
Mon, 6/1: 11:15 AM - 12:15 PM CDT
Education Sessions 
Ernest N. Morial New Orleans Convention Center 
Room: 295 
CM Credit Hours:

Description

Exposure simulation studies are a useful approach for measuring exposures in a controlled setting. They can be designed to evaluate exposures from isolated tasks, examine historical exposures, assess prospective exposures from process changes, or address regulatory requirements such as those under TSCA. While simulation studies can yield valuable information about exposure levels, several important considerations must be addressed to ensure the collected data are accurate and relevant.

This session will provide an overview of what a simulation study is, applications for simulation studies, and practical information on conducting a simulation study including goal-setting, sample collection and analysis, controls and safety, and interpretation of results. Sampling strategies will be discussed including task-based versus full-shift sampling, real-time versus media-based collection, personal versus area sampling, ventilation conditions, prescribed tasks versus typical work practices, and agent-specific concerns such as take-home exposures for particulates. Advantages, limitations and challenges of simulation studies will be discussed in the context of potential study goals. Several completed simulation studies will be utilized as case studies to illustrate concepts covered in this session. These examples will address both dermal and inhalation exposures and will feature a range of agents, including benzene, toluene, ethylbenzene, and xylene (BTEX), asbestos, and lead.

Learning Outcomes

Upon completion, the participant will be able to
• Describe an exposure simulation study.
• Identify circumstances in which simulation studies are useful in evaluating workplace exposures.
• Develop sampling strategies tailored to goals of the simulation study.
• Troubleshoot common complications associated with planning and conducting a simulation study.
• Characterize the limitations of simulation studies on simulating real-world exposure scenarios.
• Evaluate tradeoffs between study feasibility, resource constraints, and the quality or relevance of the data collected. 

Content Level

Intermediate

Core Competencies

Chemical Sampling and Instrumental Analysis
Exposure Assessment

Keywords

Aerosol and airborne particulate monitoring
Asbestos, lead, and dust
Equipment rental and repair
Exposure Assessment
Gas and vapor detection

Session Availability

In-person
OnDemand
Virtual

Targeted Audience

Professional

Transfer of Knowledge

Case Studies
Practical Application
Test/Quiz