4. GWAS of EEG oscillations unveils genetic pleiotropy between brain structure, function, and behavior
Philippe Jawinski
Presenter
Humboldt-Universität zu Berlin
Department of Psychology
Berlin
Germany
Monday, Jun 24: 5:45 PM - 7:00 PM
2959
Oral Sessions
COEX
Room: Grand Ballroom 101-102
Oscillations in neuronal brain activity play a crucial role in information processing and have been studied extensively as biological markers of human behavior and psychopathology [1]. A century ago, in 1924, Hans Berger's discovery marked the inception of a transformative era in neuroscience, leading to crucial advancements in our understanding of brain function and the corresponding behavioral phenomena [2]. Twin studies have demonstrated that individual differences in EEG oscillations are strongly driven by genetic factors [3]. However, our understanding of their molecular genetic architecture is still very limited. Here, we conducted a genome-wide association study (GWAS) of resting-state EEG oscillations to discover associated genomic loci and to examine the pleiotropic relationships with other complex traits, i.e., the links with brain structure and mental illness.
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