Enhanced inter-subject synchrony promotes phenotype prediction in naturalistic conditions

COEX 

Recent studies have suggested that naturalistic stimuli, such as movie clips, outperform rest and conventional tasks in phenotype prediction [1, 2]. Despite their promise, the impact of stimulus selection on phenotype prediction remains largely unclear. Most existing datasets of naturalistic conditions lack sufficient justifications for selecting specific stimuli, and many studies so far have used one single stimulus. Here, we investigate the impact of stimulus selection on phenotype prediction from two aspects, namely brain states (inter-subject synchrony) [3] and stimulus features. We focus on the paradigmatic case of sex classification due to the robust and well-established nature of the brain-sex relationship.