Motor phenotypes: Multivariate associations with sleep, mental health, and grey matter volume

COEX 

Motor behaviour plays an important role in our ability to interact with the world. Higher levels of physical activity and motor performance are associated with better sleep quality and mental health [1], [2]. Previous studies mainly assessed univariate associations between individual measures rather than exploring the interplay between the latent dimensions of sleep, mental health, and motor behaviour. Furthermore, the neurobiology underlying their interplay remains unclear. In this study, we aimed to assess multivariate links between motor behaviour and the combined factors of sleep and mental health. Additionally, we discerned the interindividual neuroanatomical basis of their interaction through a predictive machine-learning approach in a large-scale sample.