Spontaneous in-scanner motion is related to a dopamine D2 receptor enriched cortical network

Spontaneous movement has become a topic of increasing interest, with it being linked to widespread neural activation patterns in rodents. A potential way to study this in humans is to look at spontaneous head motion in the MRI scanner whilst recording brain activity. The fact that motion affects the data being recorded makes this challenging as it may be difficult to disentangle artifactual activity changes from motion-related ones. To attempt to circumvent this problem, we took large motions as spontaneous events and then related event-related maps to distributions of dopamine D2 receptors. This receptor type was chosen as it has been previously linked to spontaneous motion production.