How analytical flexibility affects neuroimaging results

COEX 

The analysis of neuroimaging data is complex and flexible, consisting of many steps, with multiple possible choices in each step. New methods and approaches are consistently being developed, increasing analytical flexibility, often without agreement on optimal choices. How does this analytical variability affect results in practice? This talk will describe the Neuroimaging Analysis Replication and Prediction Study (NARPS; https://www.narps.info/), in which seventy independent analysis teams tested the same pre-defined hypotheses with the same fMRI dataset, and the variability of their methods and results were examined. The implications of the findings and potential solutions will be discussed, along with related studies in other modalities and fields.