Multi-scale approaches to brain vulnerability for psychosis

COEX 

Gemma Modinos (UK), will present new data linking MRI-based markers of brain function in individuals with early- and chronic-stage schizophrenia spectrum disorders to specific cell-types and neuroreceptor systems, by using available gene expression and neuroreceptor atlases. She will also show new data on the effects of pharmacological modulation of excitation-inhibition balance on multi-modal MRI profiles in individuals at clinical high-risk for psychosis and relevant animal models.