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Brain Volumetric Changes 1 year after SG bariatric surgery.

Poster No:

2124 

Submission Type:

Abstract Submission 

Authors:

Hugo Sandoval1, Thomas O'Neill1, Deborah Clegg1, Benjamin Clapp1

Institutions:

1Texas Tech Health Science Center El Paso, El Paso, TX

First Author:

Hugo Sandoval  
Texas Tech Health Science Center El Paso
El Paso, TX

Co-Author(s):

Thomas O'Neill  
Texas Tech Health Science Center El Paso
El Paso, TX
Deborah Clegg  
Texas Tech Health Science Center El Paso
El Paso, TX
Benjamin Clapp  
Texas Tech Health Science Center El Paso
El Paso, TX

Introduction:

Obesity is one of the most significant health concerns of the twenty-first century. One of the most efficacious mechanisms to reduce body weight is the sleeve gastrectomy. The aim of this study is to analyze the postoperative anatomical changes 1year after sleeve gastrectomy (SG) in Hispanic females (HF).

Methods:

A total of 19 SG Hispanic female patients (average age 39) participated in the study. MPRAGE anatomical scans were acquired using a 3 T Siemens Skyra scanner before surgery and 1 year after SG. Cortical reconstruction and volumetric segmentation was performed with the Freesurfer image analysis suite, which is documented and freely available for download online (http://surfer.nmr.mgh.harvard.edu ). This processing method includes motion correction and averaging, removal of non-brain tissue using a hybrid watershed/surface deformation procedure, segmentation of the subcortical white matter and deep gray matter volumetric structures including hippocampus, amygdala, caudate, putamen, ventricles.

Results:

Our results indicate SG in Hispanic females results in the following structural changes: increased hippocampus, amygdala, cerebral white matter and cerebellar volumes.

Conclusions:

Structural changes in hippocampus, amygdala, cerebral white matter and cerebellar volumes take place after SG. These changes may influence perceptions and relationships with food, body habitus, and feelings associated with eating.

Neuroanatomy, Physiology, Metabolism and Neurotransmission:

Anatomy and Functional Systems 2
Cortical Anatomy and Brain Mapping
White Matter Anatomy, Fiber Pathways and Connectivity

Physiology, Metabolism and Neurotransmission:

Neurophysiology of Imaging Signals
Physiology, Metabolism and Neurotransmission Other 1

Keywords:

STRUCTURAL MRI
White Matter
Other - bariatric surgery

1|2Indicates the priority used for review
Supporting Image: Picture1.png
 

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Please indicate below if your study was a "resting state" or "task-activation” study.

Resting state

Healthy subjects only or patients (note that patient studies may also involve healthy subjects):

Patients

Was this research conducted in the United States?

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Are you Internal Review Board (IRB) certified? Please note: Failure to have IRB, if applicable will lead to automatic rejection of abstract.

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Were any human subjects research approved by the relevant Institutional Review Board or ethics panel? NOTE: Any human subjects studies without IRB approval will be automatically rejected.

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Were any animal research approved by the relevant IACUC or other animal research panel? NOTE: Any animal studies without IACUC approval will be automatically rejected.

Not applicable

Please indicate which methods were used in your research:

Functional MRI
Structural MRI

For human MRI, what field strength scanner do you use?

3.0T

Which processing packages did you use for your study?

SPM
Free Surfer

Provide references using APA citation style.

1. Clapp B, Ponce J, Corbett J, Ghanem OM, Kurian M, Rogers AM, et al. American Society for Metabolic and Bariatric Surgery 2022 estimate of metabolic and bariatric procedures performed in the United States. Surgery for Obesity and Related Diseases. 2024.

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