Exploring associations of multimodal data with cognition in Alzheimer's disease

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Abstract Information

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Please indicate below if your study was a "resting state" or "task-activation” study.

Task-activation

Healthy subjects only or patients (note that patient studies may also involve healthy subjects):

Patients

Was this research conducted in the United States?

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Were any human subjects research approved by the relevant Institutional Review Board or ethics panel? NOTE: Any human subjects studies without IRB approval will be automatically rejected.

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Were any animal research approved by the relevant IACUC or other animal research panel? NOTE: Any animal studies without IACUC approval will be automatically rejected.

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Please indicate which methods were used in your research:

Functional MRI

Structural MRI

Neuropsychological testing

For human MRI, what field strength scanner do you use?

3.0T

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SPM

Free Surfer

Provide references using APA citation style.

Düzel, E. (2011). Functional phenotyping of successful aging in long-term memory: Preserved performance in the absence of neural compensation. Hippocampus, 21(8), 803–814. https://doi.org/10.1002/hipo.20834

Jessen, F. (2018). Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer’s disease (DELCODE). Alzheimer’s Research & Therapy, 10(1), 15. https://doi.org/10.1186/s13195-017-0314-2

Lattmann-Grefe, R. (2024). Dysfunction of the episodic memory network in the Alzheimer’s disease cascade (S. 2024.10.25.620237). bioRxiv. https://doi.org/10.1101/2024.10.25.620237

Menze, I. (2024). Perivascular space enlargement accelerates in ageing and Alzheimer’s disease pathology: Evidence from a three-year longitudinal multicentre study. Alzheimer’s Research & Therapy, 16(1), 242. https://doi.org/10.1186/s13195-024-01603-8

Nemali, A. (2023). Gaussian Process-based prediction of memory performance and biomarker status in ageing and Alzheimer’s disease—A systematic model evaluation. Medical Image Analysis, 90, 102913. https://doi.org/10.1016/j.media.2023.102913

Soch, J. (2021). A comprehensive score reflecting memory-related fMRI activations and deactivations as potential biomarker for neurocognitive aging. Human Brain Mapping, 42(14), 4478–4496. https://doi.org/10.1002/hbm.25559

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