Therapeutic Efficacy and Neural Mechanisms of tACS in Depression with Suicidal Ideation

Brisbane Convention & Exhibition Centre 

Suicidal ideation is a severe symptom of depression and a critical precursor to suicide, requiring effective interventions(Grant, 2018; May, 2015). Transcranial alternating current stimulation (tACS), a novel non-invasive neuromodulation technique, has shown promise in treating neuropsychiatric disorders(Miranda, 2013; Berényi, 2018; Wang, 2022). However, its efficacy in alleviating suicidal ideation in depression and the underlying mechanisms remain unclear. This study aims to evaluate the therapeutic effects of tACS on suicidal ideation and investigate its potential mechanisms.