Using MRI to Personalize Brain Stimulation:Rationale, Practical Implications and Considerations

Emerging research indicates that many psychiatric disorders are characterized by dysfunctional brain circuits. In this talk I will briefly reiterate how this circuit-based framework has reshaped and improved the capacity to identify optimal brain stimulation targets for psychiatric disorders. I will illustrate how these circuits can be targeted on a personalized basis and briefly overview the evidence for this approach from basic and clinical research. I will then detail practical considerations around scanner parameters and neuronavigation accuracy that have implications for personalized and circuit-based targeting. Lastly, I will briefly highlight hardware solutions that provide a cheaper alternative to neuronavigation where desired.