Metabolic brain networks in the evaluation of patients with neurodegenerative disorders: rigorous validation done right

In this talk, we will present thirty year of research endeavors to identify, validate and assess metabolic brain networks at a single-subject level scaled subprofile model/principal component analysis (SSM/PCA) and discuss the added clinical value for early and accurate diagnosis and prognosis of patients with neurodegenerative disorders. We will showcase the validity and reliability of the model across different disorders, sites, and disease stages.